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Syntrix Pharmaceuticals > Blog
  • News

    Syntrix to present at 2025 Life Science Innovation Northwest (LSINW)

    April 15, 2025 - by Syntrix

    AUBURN, WASHINGTON — Syntrix Pharmaceuticals is pleased to announce that it has been invited to present development and financing goals…

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  • News

    ASCO 2024 selects SX-682 for oral podium presentation of positive first-in-class efficacy results in patients with metastatic melanoma

    May 25, 2024 - by Syntrix

    – Safety and efficacy data will be presented for first-in-class CXCR1/2 inhibitor SX-682 in combination with pembrolizumab in patients with…

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  • News

    New study finds SX-682 leads to “unprecedented” response and cures in pancreatic cancer models

    December 30, 2022 - by Syntrix

    AUBURN, WASHINGTON —A new study led by researchers at MD Anderson Cancer Center revealed for the first time that SX-682…

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  • News

    First-in-Class Investigational SX-682 Demonstrates Single-Agent Efficacy in Patients with Hypomethylating Agent Failure Myelodysplastic Syndromes

    December 8, 2022 - by Syntrix

    — Phase 1 Findings Presented in Oral Session at 2022 American Society of Hematology (ASH) Meeting Support CXCR1/2 as Promising…

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  • News

    New Study Points to SX-682 as Novel Strategy to Broadly Increase the Effectiveness of Therapies Targeting the RAS/RAF/MEK/ERK Signaling Pathway in Non-Small Cell Lung Cancer

    August 8, 2021 - by Syntrix

    A new study led by researchers at NYU Grossman School of Medicine and its Laura and Isaac Perlmutter Cancer Center…

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  • News

    Two New Reports Show SX-682 Blocks Key Immunosuppressive Tumor Cells to Enhance Checkpoint Inhibitors and NK-Based Cell Immunotherapies

    January 6, 2020 - by Syntrix

    Researchers at the Fred Hutchinson Cancer Research Center and the National Institutes of Health (NIH) independently showed SX-682 eradicates pivotal…

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  • News

    Syntrix Pharmaceuticals to Present Positive Desmetramadol Trial Results at the 2019 Pain Management SUMMIT

    October 30, 2019 - by Syntrix

    Desmetramadol trial featured on the October cover of The Journal of Pain AUBURN, WASHINGTON — Syntrix Pharmaceuticals, Inc., a leading…

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  • News

    Syntrix Announces Dosing of First Patient in Phase 1/2 Clinical Trial of SX-682 in Combination with KEYTRUDA® (pembrolizumab) in Metastatic Melanoma

    June 20, 2019 - by Syntrix

    – Initial Clinical Data Expected in First Half of 2020 – AUBURN, WASHINGTON — Syntrix Pharmaceuticals today announced that it…

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  • News

    Syntrix Reports Positive Clinical Trials Showing Desmetramadol Has the Analgesic and Side Effect Profile of Tramadol Without Its Metabolic Liabilities

    June 4, 2019 - by Syntrix

    Study successfully met its endpoints and provides basis for pivotal Phase 3 trial AUBURN, WASHINGTON — Syntrix Pharmaceuticals today announced…

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  • News

    Researchers Report SX-682 Could Enhance Multiple Forms of T Cell-Based Immunotherapies in Solid Tumors

    April 8, 2019 - by Syntrix

    Researchers at the National Institutes of Health (NIH) have shown that inhibition of myeloid-derived suppressor cell (MDSC) trafficking into mouse…

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  • News

    New Study Points to SX-682 as Strategy to Boost Immunotherapy Effectiveness in Advanced Colorectal Cancer

    March 26, 2019 - by Syntrix

    AUBURN, WASHINGTON — In collaboration with Syntrix Pharmaceuticals, researchers at the University of Texas MD Anderson Cancer Center revealed that…

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  • News

    Syntrix Announces First Patient Cohort Dosed in Phase 2 Study of Desmetramadol in Diabetic Neuropathic Pain

    March 19, 2019 - by Syntrix

    AUBURN, WASHINGTON — Syntrix Pharmaceuticals today announced the initiation of a Phase 2 study evaluating the efficacy and safety of…

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  • News

    Syntrix Wins $3.4M NIH Grant to Conduct Phase 1/2 trial of SX-682 in Myelodysplastic Syndrome

    February 4, 2019 - by Syntrix

    AUBURN, WASHINGTON — Syntrix Pharmaceuticals announced this week that it has been awarded a three-year grant worth $3.4 million from…

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  • News

    Desmetramadol featured today in new article by Research Outreach

    December 17, 2018 - by Syntrix

    Desmetramadol featured today in new article by Research Outreach entitled, “Moving beyond dangerous opioids for pain: Syntrix creates new drug…

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  • News

    Syntrix Wins U.S. Patent 10,046,002 – Method for Treating Cancer Using Chemokine Antagonists

    August 14, 2018 - by Syntrix

    Congratulations to Syntrix scientists on their latest issued patent at the United States Patent and Trademark Office.  Inventors: Maeda, Dean…

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  • News

    World Health Organization’s INN Approves “Desmetramadol” as Generic Name for Omnitram

    March 29, 2018 - by Syntrix

    Syntrix today announced that the World Health Organization’s International Nonproprietary Name (INN) group have accepted the proposed generic name “Desmetramadol”…

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  • News

    Syntrix Joins National Cancer Institute (NCI) Formulary to Help Expedite Cancer Clinical Trials – Collaboration Will Support Vice President Biden’s Cancer Moonshot Program

    November 8, 2017 - by Syntrix

    Syntrix today announced their participation in the NCI Formulary, a public-private partnership between the National Cancer Institute (NCI), part of…

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  • News

    Syntrix Doses First Subject with Omnitram to Confirm Pain Relief in Patients for Whom Tramadol is Ineffective

    October 31, 2017 - by Syntrix

    Large patient populations treated with dangerous Schedule II opioids are expected to benefit from Omnitram, a safer alternative without metabolic…

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  • News

    Syntrix Wins Three U.S. Patents for Omnitram – 9,717,700; 9,717,701; 9,808,432

    August 1, 2017 - by Syntrix

    Congratulations to Syntrix scientists on their latest issued patents at the United States Patent and Trademark Office.  ‘701 Abstract: Disclosed…

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    Syntrix
  • News

    Syntrix Wins U.S. Patent 9,707,248 – Use of Thiopyrimidinecarboxamide for Treating Cancer

    July 18, 2017 - by Syntrix

    Congratulations to Syntrix scientists on their latest issued patent at the United States Patent and Trademark Office.  Inventors: Maeda, Dean…

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  • ASCO 2024 selects SX-682 for oral podium presentation of positive first-in-class efficacy results in patients with metastatic melanoma
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