31_ABB

New Syntrix Publication: Glutathione S-Transferase P1-1 Expression Modulates Sensitivity of Human Kidney 293 Cells to Photodynamic Therapy with Hypericin

Congratulations to Syntrix scientists and collaborators at the University of Washington on their latest publication, which appeared in the journal Archives of Biochemistry and Biophysics. Title: Glutathione S-transferase P1-1 expression modulates sensitivity of human kidney 293 cells to photodynamic therapy with hypericin. Authors: Dabrowski MJ, Maeda D, Zebala J, Lu WD, Mahajan S, Kavanagh TJ, Atkins WM. Abstract: Photodynamic […]

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34_AMTPharmacodynamics

New Syntrix Publication: Pharmacodynamic Properties of Methotrexate and Aminotrexate During Weekly Therapy

Congratulations to Syntrix scientists and collaborators at the University of Medicine and Dentistry of New Jersey for their published paper in Cancer Chemotherapy and Pharmacology. Abstract excerpts: Aminopterin (AMT) has several advantages over the related antifolate methotrexate (MTX), including greater potency, complete oral bioavailability, and greater accumulation by leukemic blasts in vitro. We compared the pharmacodynamic properties of equipotent […]

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